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Case of the Week 294



What's the most likely diagnosis?

  • 73 year-old with left arm pain

  1. Tuberculosis
  2. Subclavian artery aneurysm
  3. Mesothelioma
  4. Pancoast Tumor
  5. Sarcoidosis

Additional Image-close-up of a portion of the lung

 

Additional Image

 

Close-up of the apex of the left lung


Answer:

 


4. Pancoast Tumor (Superior Sulcus Tumor)

 

 

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Pancoast Tumor


General Considerations

  • A lung tumor arising in the superior sulcus and comprising fewer than 5% of all primary lung cancers
  • Described by Henry Pancoast in 1932
  • The majority of the tumor growth is extrathoracic
  • Directly invades
    • Adjacent ribs, especially the 1st, 2nd and 3rd
    • Vertebrae
    • Brachial plexus
    • Stellate ganglion
  • Most are squamous cell carcinomas
    • Fewer than 5% are small cell carcinomas

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